Petsmile Review: The VOHC-Approved Pet Toothpaste That Actually Works

My dog Mochi hates having her teeth brushed. I've tried three different toothpastes and two types of brushes — she tolerates them at best. Then I found Petsmile, and for the first time, she actually let me finish a proper brushing session without a fight. That alone was worth the price of admission.

What Is Petsmile?

Petsmile is a professional-grade pet toothpaste brand best known for being VOHC (Veterinary Oral Health Council) approved — one of the highest endorsements a pet dental care product can earn. It's recommended by veterinary dentistry specialists and backed by clinical research, which is rare in the pet oral care space.

The Science Behind Calprox®

What sets Petsmile apart from standard pet toothpastes is their proprietary Calprox® formula. It's a non-abrasive blend of encapsulated calcium, phosphates, magnesium, and minerals — similar in composition to tooth enamel itself. Rather than scrubbing plaque off mechanically, Calprox® actually dissolves it while re-mineralizing and strengthening the enamel underneath.

That means even if your pet isn't perfectly cooperative during brushing, the formula is still doing meaningful work. For owners of reluctant patients (like Mochi), this is a genuine game-changer.

Product Range

• Toothpastes: Available in London Broil, Rotisserie Chicken, and Say Cheese flavors — pets are much more willing to accept flavors they recognize
• Dental Kits: Toothpaste + brush combo packs for a complete oral care routine
• Applicator Swabs: Ideal for cats or dogs who won't tolerate a brush — apply the paste without a fight
• Toothbrushes: Dual-ended soft bristle design for both dogs and cats

Real Results

After three weeks of consistent use, I noticed a visible difference in Mochi's teeth — cleaner looking, with less visible plaque buildup near the gumline. Her breath improved noticeably within the first week. The vets I've spoken to who carry Petsmile in-office say it's the only pet toothpaste they actively recommend to clients.

Pros

• VOHC-approved — clinically proven effectiveness
• Calprox® formula works even with imperfect application
• Pet-friendly flavors that make brushing more cooperative
• Gluten-free, silica-free, paraben-free, xylitol-free, sulfate-free
• Free shipping on $35+ orders

Cons

• Premium pricing compared to standard pet toothpastes — but worth it given the clinical backing

Final Verdict

If your vet has been nudging you to take your pet's dental health more seriously, Petsmile is where I'd start. The VOHC seal isn't handed out casually, and the Calprox® formula genuinely delivers cleaner teeth and fresher breath. Use the exclusive code below for 15% off your first order.

Shop Petsmile's full dental care range here.